abstract：STUDY DESIGN:Self-assembling peptide gel (SPG-178) provides new evidence for the role of a scaffold for treatment of the spinal cord through induction of neuroprotective factors. OBJECTIVE:To verify the reproducibility of SPG-178 as scaffold after spinal cord injury, we examine the characteristics of SPG-178 and prote...

journal_title：Spine

authors： Ando K,Imagama S,Ito Z,Kobayashi K,Hida T,Nakashima H,Ito K,Tsushima M,Ishikawa Y,Matsumoto A,Nishida K,Nishida Y,Ishiguro N

更新日期：2016-10-15 00:00:00

abstract：:The incredible career of Henry H. Bohlman, MD, spanned over four decades at University Hospitals Case Medical Center. He was an innovator and pioneer, designing several techniques for the management of several spinal pathologies while advocating the anterior approach to the spine. Dr. Bohlman's legacy is preserved in ...

journal_title：Spine

authors： Abola MV,Knapik DM,Gordon ZL,Furey CG,Marcus RE

更新日期：2016-10-15 00:00:00

abstract：STUDY DESIGN:Retrospective cohort study of the American College of Surgeons National Surgical Quality Improvement Program database from 2011 to 2012. OBJECTIVE:Minimizing the morbidity of posterior cervical fusion can be improved with identification of patient risk factors. SUMMARY OF BACKGROUND DATA:Posterior cervic...

journal_title：Spine

authors： Medvedev G,Wang C,Cyriac M,Amdur R,O'Brien J

更新日期：2016-10-01 00:00:00

abstract：STUDY DESIGN:Case report. OBJECTIVES:The aim of this study was to assess the feasibility, safety, and accuracy of a new robotic system for performing posterior C1-2 transarticular screw fixation for atlantoaxial instability. SUMMARY OF BACKGROUND DATA:C1-2 transarticular fixation is a reliable procedure. However, the...

journal_title：Spine

authors： Tian W

更新日期：2016-10-01 00:00:00

abstract：STUDY DESIGN:A retrospective analysis of the clinical outcomes of eight patients with the lumbar pars interarticulars defects treated by direct repair with the aid of intraoperative O-arm based navigation and microendoscopic techniques. OBJECTIVE:The aim of this study was to investigate the efficacy and safety of dire...

journal_title：Spine

authors： Jia M,Wang J,Zhang Z,Zheng W,Zhou Y

更新日期：2016-10-01 00:00:00

abstract：STUDY DESIGN:A prospective, randomized controlled study of patients with L5-S1 lumbar disc herniations, operated with endoscopic discectomy through an interlaminar or transforaminal approach. OBJECTIVE:To compare the results of percutaneous endoscopic lumbar discectomy in L5-S1 disc herniation through an interlaminar ...

journal_title：Spine

authors： Nie H,Zeng J,Song Y,Chen G,Wang X,Li Z,Jiang H,Kong Q

更新日期：2016-10-01 00:00:00

abstract：STUDY DESIGN:This prospective observational study included 22 patients who were diagnosed with symptomatic degenerative disc disease treated via artificial disc replacement (ADR) with a laparoscopic technique. OBJECTIVE:The current study aimed to assess the safety and efficacy of ADR using a laparoscopic technique for...

journal_title：Spine

authors： Wang W,Liu S,He G,Yan Y,Li X,Ouyang Z,Zuo J

更新日期：2016-10-01 00:00:00

abstract：STUDY DESIGN:Retrospective case-control study. OBJECTIVE:The purpose of this study was to examine the factors of postoperative paralysis in patients who have undergone thoracic ossification of posterior longitudinal ligament (OPLL) surgery. SUMMARY OF BACKGROUND DATA:A higher percentage of thoracic OPLL patients expe...

journal_title：Spine

authors： Ito Z,Matsuyama Y,Ando M,Kawabata S,Kanchiku T,Kida K,Fujiwara Y,Yamada K,Yamamoto N,Kobayashi S,Saito T,Wada K,Tadokoro N,Takahashi M,Satomi K,Shinomiya K,Tani T

更新日期：2016-10-01 00:00:00

abstract：STUDY DESIGN:A retrospective case series. OBJECTIVE:The aim of this study was to evaluate patients with cervical spine osteomyelitis who underwent multilevel (≥2) subaxial corpectomies and anterior column reconstruction and plating. SUMMARY OF BACKGROUND DATA:Neglected multilevel subaxial cervical osteomyelitis is a ...

journal_title：Spine

authors： Theologis AA,Lansdown D,McClellan RT,Chou D,Pekmezci M

更新日期：2016-09-15 00:00:00

abstract：STUDY DESIGN:A prospective study of anterior transarticular screw (ATS) fixation patients. OBJECTIVE:To develop a method to determine screw tip position through plain radiography after percutaneous ATS fixation to prevent occipitocervical joint (OCJ) violation. SUMMARY OF BACKGROUND DATA:No studies using plain radiog...

journal_title：Spine

authors： Jin HM,Xu DL,Xuan J,Chen JX,Goswami A,Chen XB,Wu AM,Chi YL,Wang XY

更新日期：2016-09-01 00:00:00

abstract：STUDY DESIGN:A single-institution, single-surgeon retrospective review. OBJECTIVE:To assess the efficacy of posterior only approach with short instrumentation and prolonged suction drainage in managing lumbar pyogenic spondylitis. SUMMARY OF BACKGROUND DATA:Several methods of posterior surgical treatment for pyogenic...

journal_title：Spine

authors： Kim YM,Choi SM

更新日期：2016-09-01 00:00:00

abstract：STUDY DESIGN:A systematic review. OBJECTIVE:The aim of this review was to evaluate the effectiveness of motor control exercise (MCE) in patients with nonspecific low back pain (LBP). SUMMARY OF BACKGROUND DATA:MCE is a common form of exercise used for managing LBP. MCE focuses on the activation of the deep trunk musc...

journal_title：Spine

authors： Saragiotto BT,Maher CG,Yamato TP,Costa LOP,Costa LCM,Ostelo RWJG,Macedo LG

更新日期：2016-08-15 00:00:00

abstract：STUDY DESIGN:The study was based on porcine posterolateral fusion model. OBJECTIVE:The study aims to prove that polyelectrolyte complex (PEC) carrier could enhance the efficacy and safety profile of bone morphogenetic protein-2 (BMP-2). SUMMARY OF BACKGROUND DATA:BMP-2 was introduced to enhance posterolateral fusion;...

journal_title：Spine

authors： Wang M,Lam RWM,Abbah SA,Hu T,Toh SY,Cool S,Bhakoo K,Li J,Goh JCH,Wong HK

更新日期：2016-08-01 00:00:00

abstract：STUDY DESIGN:Laboratory/animal-based proof of principle study. OBJECTIVE:To validate the accuracy of a magnetic resonance imaging (MRI)-guided stereotactic system for intraspinal electrode targeting and demonstrate the feasibility of such a system for controlling implantation of intraspinal electrodes. SUMMARY OF BAC...

journal_title：Spine

authors： Grahn PJ,Goerss SJ,Lujan JL,Mallory GW,Kall BA,Mendez AA,Trevathan JK,Felmlee JP,Bennet KE,Lee KH

更新日期：2016-07-01 00:00:00

abstract：STUDY DESIGN:A retrospective database analysis. OBJECTIVE:The aim of this study is to compare rates of postoperative dysphagia, length of stay, infection, and wound complications following short and long anterior cervical discectomy and fusion (ACDF) in patients who received local intraoperative steroids and those who...

journal_title：Spine

authors： Cancienne JM,Werner BC,Loeb AE,Yang SS,Hassanzadeh H,Singla A,Shen FH,Shimer AL

更新日期：2016-07-01 00:00:00

abstract：STUDY DESIGN:Ninety-six male adult CD-1 mice were randomly divided into sham, spinal cord injury (SCI) + vehicle, and SCI + IPA-3 groups. Expression of matrix metalloproteinase (MMP)-2 and MMP-9, production of tumor necrosis factors (TNF)-α and interleukin (IL)-1β, tissue edema, blood-spinal cord barrier penetrability,...

journal_title：Spine

authors： Ji X,Zhang Y,Zhang L,Chen H,Peng Y,Tang P

更新日期：2016-06-01 00:00:00

abstract：STUDY DESIGN:A retrospective analysis. OBJECTIVE:To evaluate the long-term clinical and radiographic outcomes and to investigate who achieved the successful outcomes after lumbar total disc replacement (TDR) using ProDisc II. SUMMARY OF BACKGROUND DATA:There are few evidences regarding the long-term efficacy and safe...

journal_title：Spine

authors： Park SJ,Lee CS,Chung SS,Lee KH,Kim WS,Lee JY

更新日期：2016-06-01 00:00:00

abstract：STUDY DESIGN:A translation, cross-cultural adaptation, and validation study. OBJECTIVE:The aim of this study was to translate, adapt cross-culturally, and validate the Kannada version of the Oswestry Disability Index (ODI). SUMMARY OF BACKGROUND DATA:Low back pain is recognized as an important public health problem. ...

journal_title：Spine

authors： Mohan V,G S P,Meravanigi G,N R,Yerramshetty J

更新日期：2016-06-01 00:00:00

abstract：STUDY DESIGN:A cross-sectional survey of orthopedic spine surgery fellowship directors in the United States. OBJECTIVE:The aim of this study was to investigate whether consensus exists with respect to spine-related adverse events and certain hospital-acquired conditions (HACs) or "never events." SUMMARY OF BACKGROUND...

journal_title：Spine

authors： Khaleel MA,Bono CM,White AP,Wood KB,Harris MB,Wagner K,Zurakowski D,McGuire KJ

更新日期：2016-06-01 00:00:00

abstract：STUDY DESIGN:Retrospective cohort study. OBJECTIVE:The objective of our study was to evaluate the differential impact of insulin dependence on lumbar surgery outcomes, including surgical and medical complications, total length of hospital stay, nonhome bound discharge, and unplanned readmissions. SUMMARY OF BACKGROUN...

journal_title：Spine

authors： Qin C,Kim JYS,Hsu WK

更新日期：2016-06-01 00:00:00

abstract：STUDY DESIGN:Analysis of spine-related patient education materials (PEMs) from subspecialty websites. OBJECTIVE:The aim of this study was to assess the readability of spine-related PEMs and compare to readability data from 2008. SUMMARY OF BACKGROUND DATA:Many spine patients use the Internet for health information. S...

journal_title：Spine

authors： Eltorai AEM,Cheatham M,Naqvi SS,Marthi S,Dang V,Palumbo MA,Daniels AH

更新日期：2016-06-01 00:00:00

abstract：STUDY DESIGN:A study examining the clinical protocol of scoliosis wound irrigation, demonstrating povidone-iodine's (PVI) effect on human osteoblast cells. Primary and immortal cell line osteoblasts were treated with 0.35% PVI for 3 minutes, and analyzed for proliferation rate, oxidative capacity, and mineralization. ...

journal_title：Spine

authors： Newton Ede MP,Philp AM,Philp A,Richardson SM,Mohammad S,Jones SW

更新日期：2016-05-01 00:00:00

abstract：STUDY DESIGN:A retrospective review of charts, x-rays (XRs) and computed tomography (CT) scans was performed. OBJECTIVE:To evaluate the accuracy of pedicle screw placement using a novel classification system to determine potentially significant screw misplacement. SUMMARY OF BACKGROUND DATA:The accuracy rate of pedic...

journal_title：Spine

authors： Sarwahi V,Wendolowski SF,Gecelter RC,Amaral T,Lo Y,Wollowick AL,Thornhill B

更新日期：2016-05-01 00:00:00

abstract：STUDY DESIGN:Cost-effectiveness analysis. OBJECTIVE:To examine the cost-effectiveness of operative versus non-operative treatment of type-II odontoid fractures in patients older than 64 years old. SUMMARY OF BACKGROUND DATA:Significant controversy exists regarding the optimum treatment of geriatric patients with type...

journal_title：Spine

authors： Barlow DR,Higgins BT,Ozanne EM,Tosteson AN,Pearson AM

更新日期：2016-04-01 00:00:00

abstract：STUDY DESIGN:Prospective, nonrandomized cohort. OBJECTIVE:Describe the surgical technique and clinical outcome of distraction lumbar laminoplasty with allograft bone block augmentation and interlaminar lumbar instrumented fusion (ILIF) SUMMARY OF BACKGROUND DATA.: ILIF is a recently described technique that may offer ...

journal_title：Spine

authors： Cuéllar JM,Field JS,Bae HW

更新日期：2016-04-01 00:00:00

abstract：STUDY DESIGN:This cross-sectional study was carried out on 196 adults (98 men and 98 women), aged between 18 and 91 years. OBJECTIVE:To examine whether vertebral hemangiomas (VHs) are associated with other spinal pathologies, metabolic diseases, cardiovascular diseases, cancer and past trauma, to shed light on their p...

journal_title：Spine

authors： Slon V,Peled N,Abbas J,Stein D,Cohen H,Hershkovitz I

更新日期：2016-04-01 00:00:00

abstract：:Improving spinal fusion by optimizing scaffold and surface engineering is a topic of interest for both surgeons and researchers. Concerns regarding patient safety with off-label use of bone morphogenetic protein (BMP) have increased, and patients are choosing minimally invasive spine surgery to lessen morbidity by avo...

journal_title：Spine

authors： Chaput CD

更新日期：2016-04-01 00:00:00

abstract：:Almost 20% of joint replacement implants fail at 15 to 20 years. Reports suggest that systemic effects of metal-on-metal implants and local effects of total joint arthroplasty implants contributing to implant failure are immune system based. Sometimes implant wear debris can cause implant failure resulting from bone f...

journal_title：Spine

authors： Hallab NJ

更新日期：2016-04-01 00:00:00

abstract：STUDY DESIGN:A retrospective study. OBJECTIVE:The aim of this study was to detect risk factors for Adding-on after posterior correction surgery in patients with Lenke 1 or 2 AIS, and to explore whether Adding-on Index could be used to predict Adding-on effectively. SUMMARY OF BACKGROUND DATA:Adding-on phenomenon is a...

journal_title：Spine

authors： Yang C,Li Y,Yang M,Zhao Y,Zhu X,Li M,Liu G

更新日期：2016-04-01 00:00:00

abstract：STUDY DESIGN:A pragmatic cluster randomized controlled trial in primary care. OBJECTIVE:The aim of this study was to estimate the clinical effectiveness and cost-effectiveness of a cognitive-based education program on patients with subacute or chronic low back pain (LBP) in primary care, compared to usual treatment, p...

journal_title：Spine

authors： Werner EL,Storheim K,Løchting I,Wisløff T,Grotle M

更新日期：2016-03-01 00:00:00

abstract：STUDY DESIGN:Case report. OBJECTIVE:We present a case of isolated primary epidural lumbar Ewing sarcoma and review the current literature on the standard management. We also propose laminoplasty as safe procedure in this patient population that can provide good stabilization in young people. SUMMARY OF BACKGROUND DAT...

journal_title：Spine

authors： Giner J,Isla A,Cubedo R,Tejerina E

更新日期：2016-03-01 00:00:00

abstract：STUDY DESIGN:Multicenter retrospective cohort study. OBJECTIVE:To investigate the relationship between resident involvement in the operating room and 30-day complication rates in patients undergoing single-level anterior cervical diskectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA:Although an integral part of ac...

journal_title：Spine

authors： Kim RB,Garcia RM,Smith ZA,Dahdaleh NS

更新日期：2016-03-01 00:00:00

abstract：STUDY DESIGN:In vitro experimental study. OBJECTIVE:To investigate the effect of low-intensity pulsed ultrasound (LIPUS) on the extracellular matrix (ECM) synthesis of degenerative human nucleus pulposus cells and explore the molecular mechanism. SUMMARY OF BACKGROUND DATA:LIPUS has been used successfully for bone fr...

journal_title：Spine

authors： Zhang X,Hu Z,Hao J,Shen J

更新日期：2016-03-01 00:00:00

abstract：STUDY DESIGN:Antimicrobial effect of a novel silver-impregnated pedicle screw in rabbits. OBJECTIVE:A novel spine implant model was designed to study the antimicrobial effect of a modified Titanium (Ti) pedicle screws with methicillin-resistant Staphylococcus aureus (MRSA) in multiple surgical sites in the lumbar spin...

journal_title：Spine

authors： Hazer DB,Sakar M,Dere Y,Altinkanat G,Ziyal MI,Hazer B

更新日期：2016-03-01 00:00:00

abstract：STUDY DESIGN:A prospective comparative study. OBJECTIVE:This study aimed to establish cervical spine morphometry, alignment, and range of motion (ROM) and to clarify the impact of these age-related and degenerative changes. SUMMARY OF BACKGROUND DATA:There are no studies that have evaluated differences in the results...

journal_title：Spine

authors： Machino M,Yukawa Y,Imagama S,Ito K,Katayama Y,Matsumoto T,Inoue T,Ouchida J,Tomita K,Ishiguro N,Kato F

更新日期：2016-03-01 00:00:00

abstract：STUDY DESIGN:Retrospective review. OBJECTIVE:To assess the relationship between age and complications, and report age-stratified complication rates for the surgical treatment of adult scoliosis. SUMMARY OF BACKGROUND DATA:Literature examining age and complication rates for adult scoliosis surgery is conflicting. The ...

journal_title：Spine

authors： Shaw R,Skovrlj B,Cho SK

更新日期：2016-03-01 00:00:00

abstract：STUDY DESIGN:Systematic review and meta-analysis. OBJECTIVE:To compare the treatment effects of observational studies versus randomized controlled trials (RCTs) in cervical disc arthroplasty. SUMMARY OF BACKGROUND DATA:RCTs can be logistically challenging and sometimes insufficiently generalizable; well-designed obse...

journal_title：Spine

authors： Jee YM,Bak JS,Weinlander E,Anderson PA

更新日期：2016-03-01 00:00:00

abstract：STUDY DESIGN:Retrospective multicenter database review. OBJECTIVE:The aim of this study was to evaluate national postoperative outcomes and hospital characteristics trends from 2001 to 2010 for advanced age CSM patients. SUMMARY OF BACKGROUND DATA:Recent studies show increases in US cervical spine surgeries and CSM d...

journal_title：Spine

authors： Jalai CM,Worley N,Marascalchi BJ,Challier V,Vira S,Yang S,Boniello AJ,Bendo JA,Lafage V,Passias PG

更新日期：2016-02-01 00:00:00

abstract：STUDY DESIGN:A case report. OBJECTIVE:To report a case of the lumbar giant cell tumor (GCT) utilizing a new clinical treatment modality (denosumab therapy), which showed a massive tumor reduction combined with the L4 spondylectomy. SUMMARY OF BACKGROUND DATA:There are some controversies about spinal GCT treatments. D...

journal_title：Spine

authors： de Carvalho Cavalcante RA,Silva Marques RA,dos Santos VG,Sabino E,Fraga AC Jr,Zaccariotti VA,Arruda JB,Fernandes YB

更新日期：2016-02-01 00:00:00

abstract：STUDY DESIGN:Prospective imaging study. OBJECTIVE:To clarify the frequency of positional vertebral artery (VA) occlusion using duplex ultrasonography in patients with rheumatoid arthritis (RA). SUMMARY OF BACKGROUND DATA:Some patients with upper cervical RA develop thromboembolic stroke related to positional and tran...

journal_title：Spine

authors： Tateishi Y,Tagami A,Baba H,Osaki M,Kawakami A,Akira T

更新日期：2016-01-01 00:00:00